Graphene-Based Wearable Sensors for Biomarker Detection
Recent advancements in nanotechnology have led to the development of graphene-based wearable sensors, which have shown great promise in detecting biomarkers for various diseases. The high surface area, electrical conductivity, and biocompatibility of graphene make it an ideal material for sensing applications. This study aims to investigate the potential of graphene-based wearable sensors for biomarker detection, with a focus on non-invasive and real-time monitoring of physiological parameters. Our proposed methodology involves the fabrication of graphene-based sensors using a layer-by-layer assembly technique, followed by functionalization with specific biomarker-capturing molecules. The sensors are then integrated into a wearable platform, allowing for continuous monitoring of biomarker levels in real-time.Our results show that the graphene-based wearable sensors exhibit high sensitivity and selectivity towards target biomarkers, with a detection limit of 1 ng/mL for interleukin-6 (IL-6) and 10 ng/mL for C-reactive protein (CRP). In a pilot study involving 20 healthy subjects, our sensors demonstrated a high correlation coefficient (R² = 0.95) with conventional laboratory-based assays. Furthermore, our sensors showed excellent stability and durability, with a shelf life of over 6 months and minimal drift over 1000 hours of continuous operation. The key findings of this study demonstrate the potential of graphene-based wearable sensors for biomarker detection, enabling non-invasive and real-time monitoring of physiological parameters.The broader implications of this research are significant, as it enables the development of personalized medicine and remote health monitoring systems. The ability to detect biomarkers in real-time could facilitate early disease diagnosis, treatment, and prevention, leading to improved patient outcomes and reduced healthcare costs. Furthermore, the wearable nature of these sensors could enable continuous monitoring of biomarker levels, allowing for a better understanding of disease progression and treatment efficacy. Overall, this study contributes to the growing body of research on graphene-based wearable sensors, highlighting their potential for biomarker detection and paving the way for future developments in this field.
Academic Reviewer